Curr Opin Pediatr. 2003 Jun;15(3):339-43.
How common are gastrointestinal disorders in children with autism?
Kuddo T, Nelson KB.
SourceNeuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland 20892, USA.
We could identify no report that describes the prevalence of gastrointestinal disorders in a representative group of children with a diagnosis of autism compared with appropriate controls. Thus, we found no evidence upon which to base a confident conclusion as to whether gastrointestinal symptoms are more common in children with than without autism. However, the frequency of gastrointestinal symptoms observed in population-based samples of autistic children indicate that gastrointestinal problems are not nearly as common in children with autism as reports from pediatric gastroenterology clinics suggest.
BMC Gastroenterol. 2011; 11: 22.
Published online 2011 March 16. doi: 10.1186/1471-230X-11-22. PMCID: PMC3072352
Copyright ©2011 Adams et al; licensee BioMed Central Ltd.
Gastrointestinal flora and gastrointestinal status in children with autism -- comparisons to typical children and correlation with autism severity
James B Adams,1 Leah J Johansen,1 Linda D Powell,1 David Quig,2 and Robert A Rubin3
The strong correlation of gastrointestinal symptoms with autism severity indicates that children with more severe autism are likely to have more severe gastrointestinal symptoms and vice versa. It is possible that autism symptoms are exacerbated or even partially due to the underlying gastrointestinal problems. The low level of SCFA's was partly associated with increased probiotic use, and probably partly due to either lower production (less sacchrolytic fermentation by beneficial bacteria and/or lower intake of soluble fiber) and/or greater absorption into the body (due to longer transit time and/or increased gut permeability).